Here is a list of The Hybrid Helix Books Ranked, According to Goodreads.
#1 – Shadow of Hyperion (4.66)
This book is the latest in the series and was released in September 2023, which might have an effect on the ranking.
#2 – Wistful Ascending (4.54)
From the blurb:
A superhero space opera for grownups.
For fans of Invincible and Marvel Cinematic Universe films.
If Thor and Harry Dresden combined in a transporter accident.
The il’Drach have conquered half a galaxy behind the civilization-ending Powers of their mixed-species children.
Half-human Rohan, exhausted by a decade fighting for their Empire, has paid a secret and terrible price for his freedom.
Now retired, he strives to live a quiet life towing starships for the space station Wistful. His most pressing problems are finding the perfect cup of coffee and talking to a gorgeous shuttle tech without tripping over his own tongue.
A nearby, long-dormant wormhole is opened by a shipful of scared, angry refugees, and the many eyes of the Empire focus uncomfortably on Wistful.
As scientists, spies, and assassins converge, reverting to the monster the Empire created is the surest way to protect his friends. And the surest way to lose them.