Here is a list of 5 classic science fiction book series.
Foundation by Isaac Asimov
From the blurb of Book 1:
For twelve thousand years the Galactic Empire has ruled supreme. Now it is dying. But only Hari Seldon, creator of the revolutionary science of psychohistory, can see into the future–to a dark age of ignorance, barbarism, and warfare that will last thirty thousand years. To preserve knowledge and save humankind, Seldon gathers the best minds in the Empire–both scientists and scholars–and brings them to a bleak planet at the edge of the galaxy to serve as a beacon of hope for future generations. He calls his sanctuary the Foundation.
Dune by Frank Herbert
From the blurb of Book 1:
Set on the desert planet Arrakis, Dune is the story of the boy Paul Atreides, heir to a noble family tasked with ruling an inhospitable world where the only thing of value is the “spice” melange, a drug capable of extending life and enhancing consciousness. Coveted across the known universe, melange is a prize worth killing for…
When House Atreides is betrayed, the destruction of Paul’s family will set the boy on a journey toward a destiny greater than he could ever have imagined. And as he evolves into the mysterious man known as Muad’Dib, he will bring to fruition humankind’s most ancient and unattainable dream.
Sprawl by William Gibson
From the blurb of Book 1:
Hotwired to the leading edges of art and technology, Neuromancer is a cyberpunk, science fiction masterpiece—a classic that ranks with 1984 and Brave New World as one of the twentieth century’s most potent visions of the future.
The Matrix is a world within the world, a global consensus-hallucination, the representation of every byte of data in cyberspace…
Henry Dorsett Case was the sharpest data-thief in the business, until vengeful former employees crippled his nervous system. But now a new and very mysterious employer recruits him for a last-chance run...
Hyperion Cantos by Dan Simmons
From the blurb of Book 1:
On the world called Hyperion, beyond the law of the Hegemony of Man, there waits the creature called the Shrike. There are those who worship it. There are those who fear it. And there are those who have vowed to destroy it. In the Valley of the Time Tombs, where huge, brooding structures move backward through time, the Shrike waits for them all. On the eve of Armageddon, with the entire galaxy at war, seven pilgrims set forth on a final voyage to Hyperion seeking the answers to the unsolved riddles of their lives. Each carries a desperate hope—and a terrible secret. And one may hold the fate of humanity in his hands.
Ender’s Saga by Orson Scott Card
From the blurb of Book 1:
Andrew “Ender” Wiggin thinks he is playing computer simulated war games; he is, in fact, engaged in something far more desperate. The result of genetic experimentation, Ender may be the military genius Earth desperately needs in a war against an alien enemy seeking to destroy all human life. The only way to find out is to throw Ender into ever harsher training, to chip away and find the diamond inside, or destroy him utterly. Ender Wiggin is six years old when it begins. He will grow up fast.
But Ender is not the only result of the experiment...